Currently, in order to fix or treat erectile dysfunction or as it is called in another way- impotence, widely used mainly two types of drugs. The first one is Viagra, which has in its composition of active substance sildenafil citrate, and which is the main brand of the famous company Pfizer. Second one – Cialis with active substances in its composition- tadalafil, providing the public as a result of the joint work of such companies as the giant Eli Lilly and “YCOS”. Viagra became available to consumers in 1998, and a new drug Cialis entered to the pharmacy shelves only since 2003.
Operating system of both drugs is equal and reduce blockage PDE5 (phosphodiesterase type 5 enzyme), and it has in turn cleaves another enzyme (cyclic guanosine monophosphate, which is responsible for the erection of the male genital organ). That means that men with a lack of cyclic guanosine monophosphate have reduced erectile dysfunction. And in order to raise the amount of this enzyme for a sufficient level to provide a complete erection using a very simple method, but for some reason not used for a long time. This method consists of blocking the enzyme destroys the cyclic guanosine monophosphate.
If we compare these two drugs on the pharmacokinetics, generic Cialis is more effective. It depends on two factors: the excretion of the active compound and the length of time efficiency, ie to achieve erection. Viagra such a comparison yields and the first and the second factor several times. If the actuation condition of penile erection in men taking Viagra (sildenafil) takes 3 to 5 hours, then taking Cialis (tadalafil 20mg), almost 18 hours. A preservation of the drug after administration of Viagra is usually not more than 4 hours, while Cialis for sale may act on the day before and 36 hours.
Side effects, as well as how they work, appear identical. It can happen: dizziness, nausea, diarrhea, headache, feeling a rush of blood to the head. Less may be pain in the abdomen, lower back and joints, often they occur after taking Cialis. All side effects occur mainly in the form of moderate and only after prolonged intake is significantly reduced. The only contraindication – a parallel reception of pills for the treatment of erectile dysfunction tablets for the treatment of cardiovascular diseases (nitroglycerin and any of its analogues in any form).
Anyway Viagra is a pioneer among the drugs to treat and prevent impotence, over 15 years, while it is on the sales market, had gathered a lot of negative feedback from buyers and consumers. In 2002, an American doctor, toxicologist G. Milman conducted a survey among 270 people taking these tablets, made findings and published the results in the journal “Annals of Pharmacotherapy”.
The doctor says that men who take Viagra long term, say at a lot of unpleasant side factors after taking this medicine, such as dizziness, amnesia and disorientation. 22 people interviewed complained about groundless aggression, 13 – in the desire to prove the violence, while 6 people all had a desire to kill. Such symptoms were observed only after prolonged use of the maximum dose of the drug. And on the incompatibility of Viagra with alcohol in general reported by many sources, and have at it straight base. After all, such a combination of cost the lives of many men who do not listen to the ban on combining Viagra with alcohol.
Comparing to Viagra, generic Cialis 20 mg showed more loyal results of many passable tests. There is no strict restriction on the reception together with him fat food and alcohol, but naturally only in small doses. It is more attractive to men, who for the sake of comfort in bed do not want to say goodbye to the usual way of life and to get rid of their usual menu and drinks.
So, if you do all the research findings of these two drugs, more advantages, certainly has Cialis. Remember that taking these drugs will not cure impotence. This is not a panacea for all the problems in this area. Many of the causes of male impotence are completely different and requires a different – not drug treatments. You can find generic Cialis for sale in online pharmacy.